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The objective of the Imagine University Hospital Institute (UHI) for Genetic Diseases is to improve our knowledge of genetic diseases and thus enhance patient care in children and through to adulthood. The UHI is based on world-renowned biomedical research, patient care services, a specific university teaching and training programme and the effective exploitation of scientitfic discoveries. The UHI’s partners are Université de Paris, the INSERM (Institut National de la Santé et de la Recherche Médicale – French Institute of Health and Medical Research) and the Assistance Publique – Hôpitaux de Paris (AP-HP, the Paris Public Hospitals Group, the Operator of Necker Children’s Hospital).